Hit 'em where it hurts.

"what do you have to be depressed about..."

"you can make yourself be happy..."

"I don't believe in that..."

"it's all in your head..."

"when you say you aren't motivated, "who" is thinking that? Surely you can change the way you are "thinking..."

"you need to snap out of it already..."

"what's your problem? did you take your medication today?"

"you just need go outside more..."

"if you start losing weight, you'll start to feel better..."

"you just need to keep yourself busy..."

"if you feel like this now, what is going to happen after #2?"